Transarterial chemoembolization (TACE) in the treatment of hepatocellular carcinoma of the liver - case report

Abstract

Introduction: Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver, with significant mortality and limited therapeutic options in advanced stages of the disease. In patients who are not candidates for resection or ablative procedures, transarterial chemoembolization (TACE) has established itself as standard therapy.

Case report: We show a male patient, 69 years of age, diagnosed with an extensive right hepatic lobe tumor based on the CTA of the abdomen, unsuitable for surgical resection and thermal ablation. The TACE procedure using doxorubicin and embolization material was successfully performed in the catheterization laboratory (cath lab) of the Clinic of Radiology of KCUS, after which the control CTA showed a complete therapeutic response according to mRECIST criteria.

Discussion: The case presented confirms that TACE is an effective treatment modality in patients with intermediate HCC, even in those with large tumor lesions. A multidisciplinary approach, adequate patient selection and precise intervention technique are key success factors. This case further emphasizes the need to integrate the TACE procedure with modern systemic therapies, including immunotherapy and targeted drugs.

Conclusion: The TACE method has significant therapeutic potential in the treatment of HCC, and achieving a complete response in this case highlights the importance of an individualized approach and further research aimed at optimizing the procedure.